a study of risk factors and t- score variability in romanian women with postmenopausal osteoporosis.

the purpose of this study was to analyse the prevalence of postmenopausal osteoporosis risk factors and to analyse the t-score variability in spine and hip according to the associated risk factors.this is a retrospective study (2003-2007) including 177 female patients with postmenopausal osteoporosis. the patients were separated in seven groups according to the number of risk factors per case. the t-score was compared between this groups using unpaired t-student test.the most frequent risk factor was early menopause (44.63%), followed by low consumption of dairy products (37.29%), coffee consumption (25.99%), sedentary lifestyle (20.9%), smoking (19.21%), delayed menarche (15.25%), low body mass index (10.71%), nulliparity (7.91%), alcohol consumption (0.56%). the maximum number of risk factors per case was six. the t-score decreased with increasing number of risk factors. t-score differences are statistically significant when comparing cases with 6 risk factors to cases with 5 risk factors (p=0.0315 in spine; p=0.0088 in hip), 4 risk factors (p=0.0076 in spine; p=0.043 in hip), 3 risk factors (p<0.0001 in spine; p=0.0205 in hip), 2 risk factors (p=0.0012 in spine; p<0.0001 in hip), a single risk factor (p<0.001 in spine and hip) and no risk factor (p=0.0075 in spine; p=0.0006 in hip).association of several risk factors leads to decrease of t-score so being able to avoid any such factors may contribute to a better bone mineral density. this could be achieved by the education of female population regarding postmenopausal osteoporosis risk factors, followed by adopting an appropriate lifestyle and diet.